HYPERPROLACTINEMIA: GALACTORRHEA-AMENORRHEA SYNDROME - Clinical Manifestations



The clinical manifestations of hyperprolacti­nemia depend upon the hormone level, the sex of the patient, and individual sensitivity to the lac­togenic and mammotropic effects of the hormone. In women, hyperprolactinemia results in the so-called galactorrhea-amenorrhea syndrome. Per­sistent lactation, unprovoked by breast stimula­tion, and amenorrhea are the classic features. The syndrome may appear following pregnancy or may be unrelated to pregnancy. In men, galactor­rhea can occur, but impotence and loss of libido are more frequent complaints.